Genes that determine immunology and inflammation modify the basic defect of impaired ion conductance in cystic fibrosis epithelia

BACKGROUND: The cystic fibrosis (CF) basic defect, caused by dysfunction of the apical chloride channel CFTR in the gastrointestinal and respiratory tract epithelia, has not been employed so far to support the role of CF modifier genes. METHODS: Patients were selected from 101 families with a total...

Descripción completa

Detalles Bibliográficos
Autores principales: Stanke, Frauke, Becker, Tim, Kumar, Vinod, Hedtfeld, Silke, Becker, Christian, Cuppens, Harry, Tamm, Stephanie, Yarden, Jennifer, Laabs, Ulrike, Siebert, Benny, Fernandez, Luis, Macek, Milan, Radojkovic, Dragica, Ballmann, Manfred, Greipel, Joachim, Cassiman, Jean-Jacques, Wienker, Thomas F, Tümmler, Burkhard
Formato: Texto
Lenguaje:English
Publicado: BMJ Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003880/
https://www.ncbi.nlm.nih.gov/pubmed/20837493
http://dx.doi.org/10.1136/jmg.2010.080937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003880/
https://www.ncbi.nlm.nih.gov/pubmed/20837493
http://dx.doi.org/10.1136/jmg.2010.080937

Ejemplares similares