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Analysis on the Susceptibility Genes in Two Chinese Pedigrees with Familial Parkinson's Disease

Objective. To screen the susceptibility genes in Chinese pedigrees with early-onset familial Parkinson's disease (FPD). Methods. Fifty-one genomic DNA samples extracted from two Chinese pedigrees with FPD, the alpha-synuclein genes (SNCA), the leucine-rich repeat kinase 2(LRRK2), PINK1(PTEN-ind...

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Detalles Bibliográficos
Autores principales: Xu, Changshui, Xu, Jun, Zhang, Yanmin, Ma, Jianjun, Kawakami, Hideshi, Maruyama, Hirofumi, Kamada, Masaki
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003980/
https://www.ncbi.nlm.nih.gov/pubmed/21188226
http://dx.doi.org/10.1155/2010/674740