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Assessment of Transformed Properties In Vitro and of Tumorigenicity In Vivo in Primary Keratinocytes Cultured for Epidermal Sheet Transplantation

Epidermal keratinocytes are used as a cell source for autologous and allogenic cell transplant therapy for skin burns. The question addressed here is to determine whether the culture process may induce cellular, molecular, or genetic alterations that might increase the risk of cellular transformatio...

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Detalles Bibliográficos
Autores principales: Thépot, A., Desanlis, A., Venet, E., Thivillier, L., Justin, V., Morel, A. P., DeFraipont, F., Till, M., Krutovskikh, V., Tommasino, M., Damour, O., Hainaut, P.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003988/
https://www.ncbi.nlm.nih.gov/pubmed/21188234
http://dx.doi.org/10.1155/2011/936546