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Does long-term metformin treatment increase cardiac lipoprotein lipase?
Acute activation of adenosine monophosphate–activated protein kinase (AMPK) or jumps in cardiac work increased cardiac endothelial lipoprotein lipase (LPL), yet it is unclear whether chronic AMPK activation maintains this elevated LPL. To activate AMPK chronically, metformin at low (300 mg/kg/d) and...
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Formato: | Texto |
Lenguaje: | English |
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W.B. Saunders
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004047/ https://www.ncbi.nlm.nih.gov/pubmed/20153488 http://dx.doi.org/10.1016/j.metabol.2009.12.015 |