Low levels of transforming growth factor-beta (TGF-beta) and reduced suppression of Th2-mediated inflammation in hyperreactive human onchocerciasis

Th2-biased inflammation with eosinophilia and IgE production is a hallmark of helminth infections. It is pronounced in hyperreactive onchocerciasis patients (‘sowda’ or ‘local form’), who efficiently kill microfilariae resulting in severe dermatitis and lymphadenitis. In contrast, hyporeactive patie...

Descripción completa

Detalles Bibliográficos
Autores principales: KORTEN, S., HOERAUF, A., KAIFI, J. T., BÜTTNER, D. W.
Formato: Texto
Lenguaje:English
Publicado: Cambridge University Press 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004161/
https://www.ncbi.nlm.nih.gov/pubmed/20619070
http://dx.doi.org/10.1017/S0031182010000922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004161/
https://www.ncbi.nlm.nih.gov/pubmed/20619070
http://dx.doi.org/10.1017/S0031182010000922

Ejemplares similares