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Low levels of transforming growth factor-beta (TGF-beta) and reduced suppression of Th2-mediated inflammation in hyperreactive human onchocerciasis

Th2-biased inflammation with eosinophilia and IgE production is a hallmark of helminth infections. It is pronounced in hyperreactive onchocerciasis patients (‘sowda’ or ‘local form’), who efficiently kill microfilariae resulting in severe dermatitis and lymphadenitis. In contrast, hyporeactive patie...

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Detalles Bibliográficos
Autores principales:	KORTEN, S., HOERAUF, A., KAIFI, J. T., BÜTTNER, D. W.
Formato:	Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004161/ https://www.ncbi.nlm.nih.gov/pubmed/20619070 http://dx.doi.org/10.1017/S0031182010000922

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