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Striatal Spine Plasticity in Parkinson's Disease

Striatal dopamine (DA) denervation results in a significant loss of dendritic spines on medium spiny projection neurons in Parkinson's disease. In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated parkinsonian monkeys, spines contacted either by cortical or thalamic glutamatergic terminals a...

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Detalles Bibliográficos
Autores principales: Villalba, Rosa M., Smith, Yoland
Formato: Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004242/
https://www.ncbi.nlm.nih.gov/pubmed/21179580
http://dx.doi.org/10.3389/fnana.2010.00133