PI3Kα Inhibitors That Inhibit Metastasis

Previous genetic analyses have suggested that mutations of the genes encoding PI3Kα facilitate invasion and metastasis but have less effect on primary tumor growth. These findings have major implications for therapeutics but have not been factored into pre-clinical drug development designs. Here we...

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Detalles Bibliográficos
Autores principales: Schmidt-Kittler, Oleg, Zhu, Jiuxiang, Yang, Jian, Liu, Guosheng, Hendricks, William, Lengauer, Christoph, Gabelli, Sandra B., Kinzler, Kenneth W., Vogelstein, Bert, Huso, David L., Zhou, Shibin
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004370/
https://www.ncbi.nlm.nih.gov/pubmed/21179398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004370/
https://www.ncbi.nlm.nih.gov/pubmed/21179398

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