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Recent Development of Bifunctional Small Molecules to Study Metal-Amyloid-β Species in Alzheimer's Disease

Alzheimer's disease (AD) is a multifactorial neurodegenerative disease related to the deposition of aggregated amyloid-β (Aβ) peptides in the brain. It has been proposed that metal ion dyshomeostasis and miscompartmentalization contribute to AD progression, especially as metal ions (e.g., Cu(II...

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Detalles Bibliográficos
Autores principales: Braymer, Joseph J., DeToma, Alaina S., Choi, Jung-Suk, Ko, Kristin S., Lim, Mi Hee
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004374/
https://www.ncbi.nlm.nih.gov/pubmed/21197068
http://dx.doi.org/10.4061/2011/623051