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Construction and Characterization of Insect Cell-Derived Influenza VLP: Cell Binding, Fusion, and EGFP Incorporation

We have constructed virus-like particles (VLPs) harboring hemagglutinin (HA), neuraminidase (NA), matrix protein 1 (M1) ,and proton channel protein (M2) using baculovirus as a vector in the SF9 insect cell. The size of the expressed VLP was estimated to be ~100 nm by light scattering experiment and...

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Detalles Bibliográficos
Autores principales: Pan, Yi-Shin, Wei, Hung-Ju, Chang, Chung-Chieh, Lin, Chung-Hung, Wei, Ting-Shyang, Wu, Suh-Chin, Chang, Ding-Kwo
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004410/
https://www.ncbi.nlm.nih.gov/pubmed/21197092
http://dx.doi.org/10.1155/2010/506363