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Histone Deacetylase Inhibitors in the Treatment of Hematological Malignancies and Solid Tumors

The human genome is epigenetically organized through a series of modifications to the histone proteins that interact with the DNA. In cancer, many of the proteins that regulate these modifications can be altered in both function and expression. One example of this is the family of histone deacetylas...

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Detalles Bibliográficos
Autores principales: Federico, Mario, Bagella, Luigi
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004414/
https://www.ncbi.nlm.nih.gov/pubmed/21188171
http://dx.doi.org/10.1155/2011/475641