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New developments in treatment of ovarian carcinoma: focus on trabectedin

Trabectedin is a new marine-derived compound that binds the DNA minor groove and interacts with proteins of the DNA repair machinery. Trabectedin has shown promising single-agent activity in pretreated patients with soft tissue sarcoma, and ovarian and breast cancer, and combination with various oth...

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Detalles Bibliográficos
Autores principales: Cassier, Philippe A, Duret, Aude, Trédan, Olivier, Carrabin, Nicolas, Méeus, Pierre, Treilleux, Isabelle, Guastalla, Jean-Paul, Ray-Coquard, Isabelle
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004573/
https://www.ncbi.nlm.nih.gov/pubmed/21188115
http://dx.doi.org/10.2147/CMR.S9459