Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer

CONTEXT: Resveratrol exhibits colon cancer prevention activity in animal models; it is purported to have this activity in humans and inhibit a key signaling pathway involved in colon cancer initiation, the Wnt pathway, in vitro. DESIGN: A phase I pilot study in patients with colon cancer was perform...

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Detalles Bibliográficos
Autores principales: Nguyen, Anthony V, Martinez, Micaela, Stamos, Michael J, Moyer, Mary P, Planutis, Kestutis, Hope, Christopher, Holcombe, Randall F
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004662/
https://www.ncbi.nlm.nih.gov/pubmed/21188121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004662/
https://www.ncbi.nlm.nih.gov/pubmed/21188121

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