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Results of a phase I pilot clinical trial examining the effect of plant-derived resveratrol and grape powder on Wnt pathway target gene expression in colonic mucosa and colon cancer
CONTEXT: Resveratrol exhibits colon cancer prevention activity in animal models; it is purported to have this activity in humans and inhibit a key signaling pathway involved in colon cancer initiation, the Wnt pathway, in vitro. DESIGN: A phase I pilot study in patients with colon cancer was perform...
Autores principales: | Nguyen, Anthony V, Martinez, Micaela, Stamos, Michael J, Moyer, Mary P, Planutis, Kestutis, Hope, Christopher, Holcombe, Randall F |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004662/ https://www.ncbi.nlm.nih.gov/pubmed/21188121 |
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