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Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model

BACKGROUND/AIMS: Matrix Metalloproteinases 2 is a key molecule in cellular invasion and metastasis. Mitochondrial ROS has been established as a mediator of MMP activity. Coenzyme Q(10 )contributes to intracellular ROS regulation. Coenzyme Q(10 )beneficial effects on cancer are still in controversy b...

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Detalles Bibliográficos
Autores principales: Bahar, Massih, Khaghani, Shahnaz, Pasalar, Parvin, Paknejad, Maliheh, Khorramizadeh, Mohammad Reza, Mirmiranpour, Hossein, Nejad, Siavash Gerayesh
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004807/
https://www.ncbi.nlm.nih.gov/pubmed/21118526
http://dx.doi.org/10.1186/1475-2891-9-62