High yield expression of leptospirosis vaccine candidates LigA and LipL32 in the methylotrophic yeast Pichia pastoris

BACKGROUND: Leptospirosis, a zoonosis caused by Leptospira spp., is recognized as an emergent infectious disease. Due to the lack of adequate diagnostic tools, vaccines are an attractive intervention strategy. Recombinant proteins produced in Escherichia coli have demonstrated promising results, alb...

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Detalles Bibliográficos
Autores principales: Hartwig, Daiane D, Oliveira, Thaís L, Seixas, Fabiana K, Forster, Karine M, Rizzi, Caroline, Hartleben, Cláudia P, McBride, Alan JA, Dellagostin, Odir A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004844/
https://www.ncbi.nlm.nih.gov/pubmed/21134266
http://dx.doi.org/10.1186/1475-2859-9-98

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004844/
https://www.ncbi.nlm.nih.gov/pubmed/21134266
http://dx.doi.org/10.1186/1475-2859-9-98

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