Cargando…

Involvement of lysophosphatidic acid in bone cancer pain by potentiation of TRPV1 via PKCϵ pathway in dorsal root ganglion neurons

BACKGROUND: It has been demonstrated that lysophosphatidic acid (LPA) released from injury tissue and transient receptor potential vanilloid 1 (TRPV1) receptor are implicated in the induction of chronic pain. In the present study we examined whether an interaction between LPA receptor LPA(1 )and TRP...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Hai-Li, Zhang, Yu-Qiu, Zhao, Zhi-Qi
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004845/
https://www.ncbi.nlm.nih.gov/pubmed/21118579
http://dx.doi.org/10.1186/1744-8069-6-85