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Three Ways of Combining Genotyping and Resequencing in Case-Control Association Studies

We describe three statistical results that we have found to be useful in case-control genetic association testing. All three involve combining the discovery of novel genetic variants, usually by sequencing, with genotyping methods that recognize previously discovered variants. We first consider expa...

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Detalles Bibliográficos
Autores principales: Longmate, Jeffrey A., Larson, Garrett P., Krontiris, Theodore G., Sommer, Steve S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004857/
https://www.ncbi.nlm.nih.gov/pubmed/21187953
http://dx.doi.org/10.1371/journal.pone.0014318