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Lithium Improves Hippocampal Neurogenesis, Neuropathology and Cognitive Functions in APP Mutant Mice

BACKGROUND: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive deterioration of cognitive functions, extracellular β-amyloid (Aβ) plaques and intracellular neurofibrillary tangles within neocortex and hippocampus. Adult hippocampal neurogenesis plays an import...

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Detalles Bibliográficos
Autores principales: Fiorentini, Anna, Rosi, Maria Cristina, Grossi, Cristina, Luccarini, Ilaria, Casamenti, Fiorella
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004858/
https://www.ncbi.nlm.nih.gov/pubmed/21187954
http://dx.doi.org/10.1371/journal.pone.0014382