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Towards Universal Structure-Based Prediction of Class II MHC Epitopes for Diverse Allotypes
The binding of peptide fragments of antigens to class II MHC proteins is a crucial step in initiating a helper T cell immune response. The discovery of these peptide epitopes is important for understanding the normal immune response and its misregulation in autoimmunity and allergies and also for va...
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004863/ https://www.ncbi.nlm.nih.gov/pubmed/21187956 http://dx.doi.org/10.1371/journal.pone.0014383 |