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Skeletal Muscle NADPH Oxidase Is Increased and Triggers Stretch-Induced Damage in the mdx Mouse

Recent studies have shown that oxidative stress contributes to the pathogenesis of muscle damage in dystrophic (mdx) mice. In this study we have investigated the role of NADPH oxidase as a source of the oxidative stress in these mice. The NADPH oxidase subunits gp91(phox), p67(phox) and rac 1 were i...

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Detalles Bibliográficos
Autores principales: Whitehead, Nicholas P., Yeung, Ella W., Froehner, Stanley C., Allen, David G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004864/
https://www.ncbi.nlm.nih.gov/pubmed/21187957
http://dx.doi.org/10.1371/journal.pone.0015354