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Ex vivo development, expansion and in vivo analysis of a novel lineage of dendritic cells from hematopoietic stem cells

Dendritic cells (DCs) play a key role in innate and adaptive immunity but the access to sufficient amount of DCs for basic and translational research has been limited. We established a novel ex vivo system to develop and expand DCs from hematopoietic stem/progenitor cells (HPCs). Both human and mous...

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Detalles Bibliográficos
Autores principales: Han, Shuhong, Wang, Yichen, Wang, Bei, Patel, Ekta, Okada, Starlyn, Yang, Li-Jun, Moreb, Jan S, Chang, Lung-Ji
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004889/
https://www.ncbi.nlm.nih.gov/pubmed/21106069
http://dx.doi.org/10.1186/1476-8518-8-8