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Skeletal Muscle Myofibrillar and Sarcoplasmic Protein Synthesis Rates Are Affected Differently by Altitude-Induced Hypoxia in Native Lowlanders

As a consequence to hypobaric hypoxic exposure skeletal muscle atrophy is often reported. The underlying mechanism has been suggested to involve a decrease in protein synthesis in order to conserve O(2). With the aim to challenge this hypothesis, we applied a primed, constant infusion of 1-(13)C-leu...

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Detalles Bibliográficos
Autores principales: Holm, Lars, Haslund, Mads Lyhne, Robach, Paul, van Hall, Gerrit, Calbet, Jose A. L., Saltin, Bengt, Lundby, Carsten
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004931/
https://www.ncbi.nlm.nih.gov/pubmed/21187972
http://dx.doi.org/10.1371/journal.pone.0015606