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Tailoring Adjuvant Endocrine Therapy for Postmenopausal Breast Cancer: A CYP2D6 Multiple-Genotype-Based Modeling Analysis and Validation

PURPOSE: Previous studies have suggested that postmenopausal women with breast cancer who present with wild-type CYP2D6 may actually have similar or superior recurrence-free survival outcomes when given tamoxifen in place of aromatase inhibitors (AIs). The present study established a CYP2D6 multiple...

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Detalles Bibliográficos
Autores principales: Yu, Ke-Da, Huang, A-Ji, Shao, Zhi-Ming
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004945/
https://www.ncbi.nlm.nih.gov/pubmed/21187922
http://dx.doi.org/10.1371/journal.pone.0015649