p38 MAPK and JNK Antagonistically Control Senescence and Cytoplasmic p16INK4A Expression in Doxorubicin-Treated Endothelial Progenitor Cells

Patients treated with low-dose anthracyclines often show late onset cardiotoxicity. Recent studies suggest that this form of cardiotoxicity is the result of a progenitor cell disease. In this study we demonstrate that Cord Blood Endothelial Progenitor Cells (EPCs) exposed to low, sub-apoptotic doses...

Descripción completa

Detalles Bibliográficos
Autores principales: Spallarossa, Paolo, Altieri, Paola, Barisione, Chiara, Passalacqua, Mario, Aloi, Concetta, Fugazza, Giuseppina, Frassoni, Francesco, Podestà, Marina, Canepa, Marco, Ghigliotti, Giorgio, Brunelli, Claudio
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004949/
https://www.ncbi.nlm.nih.gov/pubmed/21187925
http://dx.doi.org/10.1371/journal.pone.0015583

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004949/
https://www.ncbi.nlm.nih.gov/pubmed/21187925
http://dx.doi.org/10.1371/journal.pone.0015583

Ejemplares similares