Cargando…
p38 MAPK and JNK Antagonistically Control Senescence and Cytoplasmic p16INK4A Expression in Doxorubicin-Treated Endothelial Progenitor Cells
Patients treated with low-dose anthracyclines often show late onset cardiotoxicity. Recent studies suggest that this form of cardiotoxicity is the result of a progenitor cell disease. In this study we demonstrate that Cord Blood Endothelial Progenitor Cells (EPCs) exposed to low, sub-apoptotic doses...
Autores principales: | Spallarossa, Paolo, Altieri, Paola, Barisione, Chiara, Passalacqua, Mario, Aloi, Concetta, Fugazza, Giuseppina, Frassoni, Francesco, Podestà, Marina, Canepa, Marco, Ghigliotti, Giorgio, Brunelli, Claudio |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3004949/ https://www.ncbi.nlm.nih.gov/pubmed/21187925 http://dx.doi.org/10.1371/journal.pone.0015583 |
Ejemplares similares
-
Inhibition of Doxorubicin-Induced Senescence by PPARδ Activation Agonists in Cardiac Muscle Cells: Cooperation between PPARδ and Bcl6
por: Altieri, Paola, et al.
Publicado: (2012) -
Doxorubicin Impairs the Insulin-Like Growth Factor-1 System and Causes Insulin-Like Growth Factor-1 Resistance in Cardiomyocytes
por: Fabbi, Patrizia, et al.
Publicado: (2015) -
Testosterone Antagonizes Doxorubicin‐Induced Senescence of Cardiomyocytes
por: Altieri, Paola, et al.
Publicado: (2016) -
C242T Polymorphism in CYBA Gene (p22(phox)) and Risk of Coronary Artery Disease in a Population of Caucasian Italians
por: Nasti, Sabina, et al.
Publicado: (2006) -
CD14CD16 Monocyte Subset Levels in Heart Failure Patients
por: Barisione, Chiara, et al.
Publicado: (2010)