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PET imaging of α(v)β(3) integrin expression in tumours with (68)Ga-labelled mono-, di- and tetrameric RGD peptides

PURPOSE: Due to the restricted expression of α(v)β(3) in tumours, α(v)β(3) is considered a suitable receptor for tumour targeting. In this study the α(v)β(3)-binding characteristics of (68)Ga-labelled monomeric, dimeric and tetrameric RGD peptides were determined and compared with their (111)In-labe...

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Detalles Bibliográficos
Autores principales: Dijkgraaf, Ingrid, Yim, Cheng-Bin, Franssen, Gerben M., Schuit, Robert C., Luurtsema, Gert, Liu, Shuang, Oyen, Wim J. G., Boerman, Otto C.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005123/
https://www.ncbi.nlm.nih.gov/pubmed/20857099
http://dx.doi.org/10.1007/s00259-010-1615-x