Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9

Recognition of endogenous DNA and RNA by cells expressing TLR7 and TLR9 is an important contributor to the pathogenesis of systemic lupus erythematosus and has been suggested to contribute to cutaneous lupus and to a group of related inflammatory skin diseases termed interface dermatitis. We have de...

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Detalles Bibliográficos
Autores principales: Guiducci, Cristiana, Tripodo, Claudio, Gong, Mei, Sangaletti, Sabina, Colombo, Mario P., Coffman, Robert L., Barrat, Franck J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005224/
https://www.ncbi.nlm.nih.gov/pubmed/21115693
http://dx.doi.org/10.1084/jem.20101048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005224/
https://www.ncbi.nlm.nih.gov/pubmed/21115693
http://dx.doi.org/10.1084/jem.20101048

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