Cargando…

Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9–driven antiinflammatory cytokine production

The interleukin 1 receptor (IL-1R) and the Toll-like receptors (TLRs) are highly homologous innate immune receptors that provide the first line of defense against infection. We show that IL-1R type I (IL-1RI) is essential for TLR9-dependent activation of tumor necrosis factor receptor-associated fac...

Descripción completa

Detalles Bibliográficos
Autores principales: González-Navajas, Jose M., Law, Jason, Nguyen, Kim Phung, Bhargava, Meha, Corr, Mary Patricia, Varki, Nissi, Eckmann, Lars, Hoffman, Hal M., Lee, Jongdae, Raz, Eyal
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005235/
https://www.ncbi.nlm.nih.gov/pubmed/21115691
http://dx.doi.org/10.1084/jem.20101326