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Genetic Risk Reclassification for Type 2 Diabetes by Age Below or Above 50 Years Using 40 Type 2 Diabetes Risk Single Nucleotide Polymorphisms

OBJECTIVE: To test if knowledge of type 2 diabetes genetic variants improves disease prediction. RESEARCH DESIGN AND METHODS: We tested 40 single nucleotide polymorphisms (SNPs) associated with diabetes in 3,471 Framingham Offspring Study subjects followed over 34 years using pooled logistic regress...

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Detalles Bibliográficos
Autores principales: de Miguel-Yanes, Jose M., Shrader, Peter, Pencina, Michael J., Fox, Caroline S., Manning, Alisa K., Grant, Richard W., Dupuis, Josèe, Florez, Jose C., D'Agostino, Ralph B., Cupples, L. Adrienne, Meigs, James B.
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005447/
https://www.ncbi.nlm.nih.gov/pubmed/20889853
http://dx.doi.org/10.2337/dc10-1265