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An Antithrombin-Heparin Complex Increases the Anticoagulant Activity of Fibrin Clots
Clotting blood contains fibrin-bound thrombin, which is a major source of procoagulant activity leading to clot extension and further activation of coagulation. When bound to fibrin, thrombin is protected from inhibition by antithrombin (AT) + heparin but is neutralized when AT and heparin are coval...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005802/ https://www.ncbi.nlm.nih.gov/pubmed/22820671 http://dx.doi.org/10.1155/2008/639829 |