Stability and Membrane Orientation of the Fukutin Transmembrane Domain: A Combined Multiscale Molecular Dynamics and Circular Dichroism Study

[Image: see text] The N-terminal domain of fukutin-I has been implicated in the localization of the protein in the endoplasmic reticulum and Golgi Apparatus. It has been proposed to mediate this through its interaction with the thinner lipid bilayers found in these compartments. Here we have employe...

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Detalles Bibliográficos
Autores principales: Holdbrook, Daniel A., Leung, Yuk Ming, Piggot, Thomas J., Marius, Phedra, Williamson, Philip T. F., Khalid, Syma
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005826/
https://www.ncbi.nlm.nih.gov/pubmed/21105749
http://dx.doi.org/10.1021/bi101743w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005826/
https://www.ncbi.nlm.nih.gov/pubmed/21105749
http://dx.doi.org/10.1021/bi101743w

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