Inhibition of Epidermal Growth Factor Receptor and PI3K/Akt Signaling Suppresses Cell Proliferation and Survival through Regulation of Stat3 Activation in Human Cutaneous Squamous Cell Carcinoma

Recent studies have emphasized the important role of Stat3 activation in a number of human tumors from the viewpoint of its oncogenic and antiapoptotic activity. In this study, we examined the role and related signaling molecules of Stat3 in the carcinogenesis of human cutaneous squamous cell carcin...

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Detalles Bibliográficos
Autores principales: Bito, Toshinori, Sumita, Nahoko, Ashida, Masashi, Budiyanto, Arief, Ueda, Masato, Ichihashi, Masamitsu, Tokura, Yoshiki, Nishigori, Chikako
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005828/
https://www.ncbi.nlm.nih.gov/pubmed/21197106
http://dx.doi.org/10.1155/2011/874571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005828/
https://www.ncbi.nlm.nih.gov/pubmed/21197106
http://dx.doi.org/10.1155/2011/874571

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