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Protective Role of rAAV-NDI1, Serotype 5, in an Acute MPTP Mouse Parkinson's Model

Defects in mitochondrial proton-translocating NADH-quinone oxidoreductase (complex I) have been implicated in a number of acquired and hereditary diseases including Leigh's syndrome and more recently Parkinson's disease. A limited number of strategies have been attempted to repair the dama...

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Detalles Bibliográficos
Autores principales: Barber-Singh, Jennifer, Seo, Byoung Boo, Matsuno-Yagi, Akemi, Yagi, Takao
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005838/
https://www.ncbi.nlm.nih.gov/pubmed/21188192
http://dx.doi.org/10.4061/2011/438370