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Loss of Function of E-Cadherin in Embryonic Stem Cells and the Relevance to Models of Tumorigenesis
E-cadherin is the primary cell adhesion molecule within the epithelium, and loss of this protein is associated with a more aggressive tumour phenotype and poorer patient prognosis in many cancers. Loss of E-cadherin is a defining characteristic of epithelial-mesenchymal transition (EMT), a process a...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Hindawi Publishing Corporation
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005858/ https://www.ncbi.nlm.nih.gov/pubmed/21197469 http://dx.doi.org/10.1155/2011/352616 |