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Loss of Function of E-Cadherin in Embryonic Stem Cells and the Relevance to Models of Tumorigenesis

E-cadherin is the primary cell adhesion molecule within the epithelium, and loss of this protein is associated with a more aggressive tumour phenotype and poorer patient prognosis in many cancers. Loss of E-cadherin is a defining characteristic of epithelial-mesenchymal transition (EMT), a process a...

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Detalles Bibliográficos
Autores principales:	Mohamet, Lisa, Hawkins, Kate, Ward, Christopher M.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005858/ https://www.ncbi.nlm.nih.gov/pubmed/21197469 http://dx.doi.org/10.1155/2011/352616

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