The interplay between evolution, regulation and tissue specificity in the Human Hereditary Diseasome

BACKGROUND: Human disease genes can be distinguished from essential (embryonically lethal) and non-disease genes using gene attributes. Such attributes include gene age, tissue specificity of expression, regulatory capacity, sequence length, rate of sequence variation and capacity for interaction. T...

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Detalles Bibliográficos
Autores principales: Nagaraj, Shivashankar H, Ingham, Aaron, Reverter, Antonio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005915/
https://www.ncbi.nlm.nih.gov/pubmed/21143807
http://dx.doi.org/10.1186/1471-2164-11-S4-S23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005915/
https://www.ncbi.nlm.nih.gov/pubmed/21143807
http://dx.doi.org/10.1186/1471-2164-11-S4-S23

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