Cargando…
The interplay between evolution, regulation and tissue specificity in the Human Hereditary Diseasome
BACKGROUND: Human disease genes can be distinguished from essential (embryonically lethal) and non-disease genes using gene attributes. Such attributes include gene age, tissue specificity of expression, regulatory capacity, sequence length, rate of sequence variation and capacity for interaction. T...
| Autores principales: | , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005915/ https://www.ncbi.nlm.nih.gov/pubmed/21143807 http://dx.doi.org/10.1186/1471-2164-11-S4-S23 |