Inhibition of the NEMO/IKKβ association complex formation, a novel mechanism associated with the NF-κB activation suppression by Withania somnifera’s key metabolite withaferin A

BACKGROUND: Nuclear Factor kappa B (NF-κB) is a transcription factor involved in the regulation of cell signaling responses and is a key regulator of cellular processes involved in the immune response, differentiation, cell proliferation, and apoptosis. The constitutive activation of NF-κB contribut...

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Detalles Bibliográficos
Autores principales: Grover, Abhinav, Shandilya, Ashutosh, Punetha, Ankita, Bisaria, Virendra S, Sundar, Durai
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005936/
https://www.ncbi.nlm.nih.gov/pubmed/21143809
http://dx.doi.org/10.1186/1471-2164-11-S4-S25

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005936/
https://www.ncbi.nlm.nih.gov/pubmed/21143809
http://dx.doi.org/10.1186/1471-2164-11-S4-S25

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