Identification of Urinary Biomarkers of Colon Inflammation in IL10(−/−) Mice Using Short-Column LCMS Metabolomics

The interleukin-10-deficient (IL10(−/−)) mouse develops colon inflammation in response to normal intestinal microflora and has been used as a model of Crohn's disease. Short-Column LCMS metabolite profiling of urine from IL10(−/−) and wild-type (WT) mice was used, in two independent experiments...

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Detalles Bibliográficos
Autores principales: Otter, Don, Cao, Mingshu, Lin, Hui-Ming, Fraser, Karl, Edmunds, Shelley, Lane, Geoff, Rowan, Daryl
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005964/
https://www.ncbi.nlm.nih.gov/pubmed/21188174
http://dx.doi.org/10.1155/2011/974701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005964/
https://www.ncbi.nlm.nih.gov/pubmed/21188174
http://dx.doi.org/10.1155/2011/974701

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