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Identification of Urinary Biomarkers of Colon Inflammation in IL10(−/−) Mice Using Short-Column LCMS Metabolomics
The interleukin-10-deficient (IL10(−/−)) mouse develops colon inflammation in response to normal intestinal microflora and has been used as a model of Crohn's disease. Short-Column LCMS metabolite profiling of urine from IL10(−/−) and wild-type (WT) mice was used, in two independent experiments...
Autores principales: | Otter, Don, Cao, Mingshu, Lin, Hui-Ming, Fraser, Karl, Edmunds, Shelley, Lane, Geoff, Rowan, Daryl |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005964/ https://www.ncbi.nlm.nih.gov/pubmed/21188174 http://dx.doi.org/10.1155/2011/974701 |
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