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Core transcription factors, Oct4, Sox2 and Nanog, individually form complexes with nucleophosmin (Npm1) to control embryonic stem (ES) cell fate determination
Embryonic stem (ES) cells have therapeutic potential in regenerative medicine, although the molecular mechanism controlling their pluripotency is not completely understood. Depending on interaction partners most proteins can be involved in several different cellular mechanisms. We screened for novel...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Impact Journals LLC
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006024/ https://www.ncbi.nlm.nih.gov/pubmed/21076177 |