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Fexinidazole – A New Oral Nitroimidazole Drug Candidate Entering Clinical Development for the Treatment of Sleeping Sickness

BACKGROUND: Human African trypanosomiasis (HAT), also known as sleeping sickness, is a fatal parasitic disease caused by trypanosomes. Current treatment options for HAT are scarce, toxic, no longer effective, or very difficult to administer, in particular for the advanced, fatal stage of the disease...

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Detalles Bibliográficos
Autores principales: Torreele, Els, Bourdin Trunz, Bernadette, Tweats, David, Kaiser, Marcel, Brun, Reto, Mazué, Guy, Bray, Michael A., Pécoul, Bernard
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006138/
https://www.ncbi.nlm.nih.gov/pubmed/21200426
http://dx.doi.org/10.1371/journal.pntd.0000923