Subversion of Innate Defenses by the Interplay between DENV and Pre-Existing Enhancing Antibodies: TLRs Signaling Collapse

BACKGROUND: The phenomenon of antibody dependent enhancement as a major determinant that exacerbates disease severity in DENV infections is well accepted. While the detailed mechanism of antibody enhanced disease severity is unclear, evidence suggests that it is associated with both increased DENV i...

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Detalles Bibliográficos
Autores principales: Modhiran, Naphak, Kalayanarooj, Siripen, Ubol, Sukathida
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006139/
https://www.ncbi.nlm.nih.gov/pubmed/21200427
http://dx.doi.org/10.1371/journal.pntd.0000924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006139/
https://www.ncbi.nlm.nih.gov/pubmed/21200427
http://dx.doi.org/10.1371/journal.pntd.0000924

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