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Sex- and Diet-Specific Changes of Imprinted Gene Expression and DNA Methylation in Mouse Placenta under a High-Fat Diet

BACKGROUND: Changes in imprinted gene dosage in the placenta may compromise the prenatal control of nutritional resources. Indeed monoallelic behaviour and sensitivity to changes in regional epigenetic state render imprinted genes both vulnerable and adaptable. METHODS AND FINDINGS: We investigated...

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Detalles Bibliográficos
Autores principales: Gallou-Kabani, Catherine, Gabory, Anne, Tost, Jörg, Karimi, Mohsen, Mayeur, Sylvain, Lesage, Jean, Boudadi, Elsa, Gross, Marie-Sylvie, Taurelle, Julien, Vigé, Alexandre, Breton, Christophe, Reusens, Brigitte, Remacle, Claude, Vieau, Didier, Ekström, Tomas J., Jais, Jean-Philippe, Junien, Claudine
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006175/
https://www.ncbi.nlm.nih.gov/pubmed/21200436
http://dx.doi.org/10.1371/journal.pone.0014398