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Functional Neurokinin and NMDA Receptor Activity in an Animal Naturally Lacking Substance P: The Naked Mole-Rat
Naked mole-rats are extremely unusual among mammals in that their cutaneous C-fibers lack the neuropeptide Substance P (SP). In other mammals, SP plays an important role in nociception: it is released from C-fibers onto spinal neurons where it facilitates NMDA receptor activity and causes sensitizat...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006196/ https://www.ncbi.nlm.nih.gov/pubmed/21200438 http://dx.doi.org/10.1371/journal.pone.0015162 |