Functional Neurokinin and NMDA Receptor Activity in an Animal Naturally Lacking Substance P: The Naked Mole-Rat

Naked mole-rats are extremely unusual among mammals in that their cutaneous C-fibers lack the neuropeptide Substance P (SP). In other mammals, SP plays an important role in nociception: it is released from C-fibers onto spinal neurons where it facilitates NMDA receptor activity and causes sensitizat...

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Detalles Bibliográficos
Autores principales: Brand, Antje, Smith, Ewan St. J., Lewin, Gary R., Park, Thomas J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006196/
https://www.ncbi.nlm.nih.gov/pubmed/21200438
http://dx.doi.org/10.1371/journal.pone.0015162

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