AAV Vector-Mediated Overexpression of CB1 Cannabinoid Receptor in Pyramidal Neurons of the Hippocampus Protects against Seizure-Induced Excitoxicity

The CB1 cannabinoid receptor is the most abundant G-protein coupled receptor in the brain and a key regulator of neuronal excitability. There is strong evidence that CB1 receptor on glutamatergic hippocampal neurons is beneficial to alleviate epileptiform seizures in mouse and man. Therefore, we hyp...

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Detalles Bibliográficos
Autores principales: Guggenhuber, Stephan, Monory, Krisztina, Lutz, Beat, Klugmann, Matthias
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006205/
https://www.ncbi.nlm.nih.gov/pubmed/21203567
http://dx.doi.org/10.1371/journal.pone.0015707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006205/
https://www.ncbi.nlm.nih.gov/pubmed/21203567
http://dx.doi.org/10.1371/journal.pone.0015707

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