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Phosphorylation-Dependent Protein Interaction with Trypanosoma brucei 14-3-3 Proteins that Display Atypical Target Recognition

BACKGROUND: The 14-3-3 proteins are structurally conserved throughout eukaryotes and participate in protein kinase signaling. All 14-3-3 proteins are known to bind to evolutionally conserved phosphoserine-containing motifs (modes 1 and/or 2) with high affinity. In Trypanosoma brucei, 14-3-3I and II...

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Detalles Bibliográficos
Autores principales: Inoue, Masahiro, Yasuda, Kouichi, Uemura, Haruki, Yasaka, Natsumi, Inoue, Hiroshi, Sei, Yoshitatsu, Horikoshi, Nobuo, Fukuma, Toshihide
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006207/
https://www.ncbi.nlm.nih.gov/pubmed/21203569
http://dx.doi.org/10.1371/journal.pone.0015566