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Factors important in evolutionary shaping of immunoglobulin gene loci
BACKGROUND: The extraordinary diversity characterizing the antibody repertoire is generated by both evolution and lymphocyte development. Much of this diversity is due to the existence of immunoglobulin (Ig) variable region gene segment libraries, which were diversified during evolution and, in high...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006366/ https://www.ncbi.nlm.nih.gov/pubmed/21134249 http://dx.doi.org/10.1186/1745-7580-6-13 |